A double-blind, randomized study of the efficacy of tapering programmed intermittent epidural bolus (t-PIEB) in video-assisted thoracic surgery (Pilot study)

A double-blind, randomized study of the efficacy of tapering programmed intermittent epidural bolus (t-PIEB) in video-assisted thoracic surgery (Pilot study) - Efficacy of t-PIEB in video-assisted thoracic surgery (Pilot study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049027

Enrollment

Registered

2022-09-26

Start date

2022-10-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing video-assisted thoracic surgery for lung cancer

Interventions

Postoperative epidural anesthesia with tapering programmed intermittent epidural bolus using a battery-powered infusion pump until 72 hours postoperatively Postoperative epidural anesthesia with conti

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients between 20 and 80 years old. Patients in American Society of Anesthesiologists Physical State of I-III. Patients scheduled for elective video-assisted thoracic surgery for lung cancer under general anesthesia with epidural anesthesia. Patients who can give their written consent to participate in this study.

Exclusion criteria

Exclusion criteria: Patients with severe diabetes mellitus (HbA1c > 8.4). Patients whose procedure is changed to thoracotomy during surgery. Patients with the inadequate effect of epidural anesthesia at the end of general anesthesia. Patients considered unsuitable by anesthesiologists.

Design outcomes

Primary

Measure	Time frame
Doses of patient-controlled analgesia at 24, 48, and 72 hours postoperatively	—

Countries

Japan

Contacts

Public ContactShiho Satomi

Hiroshima University Department of Anesthesiology and Critical Care

yasuo223@hiroshima-u.ac.jp082-257-5267

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026