dedifferentiated low-grade osteosarcoma(DLOS)
Conditions
Interventions
None listed
Sponsors
Nara Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: We included only studies that reported mortality and event rates, such as local recurrence and distant metastasis, after surgery alone or surgery and (neo-)adjuvant chemotherapy for localized DLOS without distant metastasis at diagnosis.
Exclusion criteria
Exclusion criteria: (1) Patients with distant metastasis at the time of DLOS diagnosis were excluded. Studies that did not specify mortality or event rates such as local recurrence or distant metastasis, or did not have a comparison group were also excluded. (2) Patients who underwent surgery alone for primary DLOS and received palliative chemotherapy for distant metastases that developed during the course of the disease were classified into the surgery-only group without adjuvant chemotherapy. (3) Only English- and Japanese-language literature was included, with no restriction on year of publication. Only human subjects were included and animals were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mortality and event rates, including local recurrence and distant metastasis | — |
Countries
Japan,Europe
Contacts
Public ContactShinji Tsukamoto
Nara Medical University Department of Orthopaedic Surgery
Outcome results
None listed