peripheral neuropathic pain
Conditions
Interventions
intravenous regionallidocaineinfusion(3 times)
intravenous regional lidocain with steroid infusion(3 times)
itravenous regional lidocaine with dexmedetomijin infusion(3 times)
oral Mirogabalin(4weeks)
Sponsors
Department of Anesthesiology & Critical Care Medicine Faculty of Medicine, Saga University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients meeting diagnostic criteria for peripheral neuropathic pain, such as Pain DETECT 2) Patients who have never been treated for neuropathic pain 3)Patients who can communicate well.
Exclusion criteria
Exclusion criteria: 1)Pregnant patients or patients of childbearing potential 2) Patients who declared non-participation in the study 3) Patients with significant psychosocial factors 4) Patients who are unable to communicate 5) Patients with coexisting diseases that may cause neurological disorders such as diabetes mellitus (6) Patients who are in court or in litigation due to accidents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood levels of cytokines (IL-27, IL-10, TNFarfa, IL-1beta) and Mincle before and after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS (Visual Analogue Scale) measurement, temperature/cold pain measurement, pain-responsive current, and minimal sensing current using a quantitative sensory/algesic analyzer before and after treatment | — |
Countries
Japan
Contacts
Public ContactNaomi Hirakakwa
Faculty of Medicine, Saga Uniiversity Anesthesiology and Critical Care Medicine
Outcome results
None listed