The relationship between thyroid function and growth in Japanese children with congenital hypothyroidism

The relationship between thyroid function and growth in Japanese children with congenital hypothyroidism: A retrospective cohort study - The relationship between thyroid function and growth in Japanese children with congenital hypothyroidism: A retrospective cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048971

Enrollment

300

Registered

2022-09-20

Start date

2021-01-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital hypothyroidism

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: People over 10years with congenital hypothyroidism detected by newborn screening and treated by levothyroxine natrium

Exclusion criteria

Exclusion criteria: People who refuse to participate in the study People who were born with a birth weight under 2,000g People with some malformation syndrome People received replacement therapy other than thyroid hormone Central hypothyroidism People who are judged by their physicians in charge to be ineligible for any reason

Design outcomes

Primary

Measure	Time frame
The age of adiposity rebound in Japanese children with congenital hypothyroidism	—

Secondary

Measure	Time frame
BMI at 15-18 years Thyroid function at newborn screening, the first visit, and the initiation of treatment Initial levothyroxine dose Distal femoral epiphysis at the first visit	—

Countries

Japan

Contacts

Public ContactKanako Nakayama

Hokkaido Univerisity Hospital Department of Pediatrics

kananaka-ped@med.hokudai.ac.jp011-706-5954

Outcome results