Frontotemporal lobar degeneration
Conditions
Interventions
tau-positive group
tau-negative group
Sponsors
Osaka University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Those who have at least one symptom of Possible bvFTD in the international diagnostic criteria for bvFTD (Rascovsky K et al, 2011) or at least one verbal symptom in Neary's diagnostic criteria for SD/PNFA (Neary D et al, 1998) and are suspected to have FTLD. Those whose age is 35 years old or older and less than 90 years old at the time of consent. Those who have given written consent to participate.
Exclusion criteria
Exclusion criteria: Women who are during pregnancy or breastfeeding. Those who have cerebrovascular disorders that may affect the results of tau PET. Those who are judged to be inappropriate for participation in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical characteristics | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB), Addenbrooke's Cognitive Examination (ACE-R), Western Aphasia Battery (WAB), Neuropsychiatric Inventory (NPI), Stereotypy Rating Inventory (SRI), Cambridge Behavioral Inventory (CBI), Everyday Memory Checklist (EMC), Geriatric depression scale (GDS), the Lawton Instrumental Activities of Daily Living Scale (IADL), Physical Self-Maintenance Scale (PSMS), Clinical Dementia Rating (CDR), cranial MRI, brain SPECT | — |
Countries
Japan
Contacts
Public ContactShunsuke Sato
Osaka University Graduate School of Medicine Department of Psychiatry
Outcome results
None listed