Relationship between periodontitis and mild cognitive impairment

Relationship between periodontitis and mild cognitive impairment: Pilot intervention study - Relationship between periodontitis and mild cognitive impairment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048936

Enrollment

Registered

2022-09-30

Start date

2022-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis and mild cognitive impairment

Interventions

Periodontitis treatment (mostly 3 times in 24 weeks)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosed as mild cognitive impairment (MMSE 24-27, and MoCA 25 or less)

Exclusion criteria

Exclusion criteria: 1)Received anti-dementia drug treatment or periodontal disease treatment within the past 6 months 2)edentulous person 3)Hypertension, untreated at the time of consent 4)Hyperlipidemia, untreated at time of consent 5)diabetes mellitus, untreated at time of consent

Design outcomes

Primary

Measure	Time frame
Mini-Mental State Examination (MMSE) (Before the beginning of periodontitis treatment and 24 weeks after the beginning of periodontitis treatment)	—

Secondary

Measure	Time frame
Montreal Cognitive Assessment (MoCA) Clock Drawing Test (CDT)	—

Countries

Japan

Contacts

Public ContactShinsuke Yoshihara

Asahikawa Medical University Department of Psychiatry

syoshi@asahikawa-med.ac.jp0166-68-2473

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026