An exploratory clinical study on relations between gut microbiota and osteoporosis

An exploratory clinical study on relations between gut microbiota and osteoporosis - An exploratory clinical study on relations between gut microbiota and osteoporosis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048918

Enrollment

Registered

2022-09-12

Start date

2022-07-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Postmenopausal women aged 65 older diagnosed with osteoporosis or normal, who understand the purpose of this research and obtain written consent

Exclusion criteria

Exclusion criteria: 1.Subjects taking steroids, antibiotics, proton pump inhibitors (Nexium, Takepron, Omeprazole, etc.) 2.Subjects with idiopathic osteoporosis, femoral neck fracture, bone tumor, rheumatoid arthritis, diabetes, chronic kidney disease 3.Subjects who have difficulty collecting specimens 4.Subjects judged by the principal investigator to be unsuitable as research subjects

Design outcomes

Primary

Measure	Time frame
Differences in the gut microbiota genes and blood metabolites in osteoporosis patients and healthy individuals	—

Secondary

Measure	Time frame
1.Relationship between gut microbiota genes and gut microbiota 2.Relationship between gut microbiota genes and blood metabolites and bone metabolism markers and bone density 3.Relationship between analysis results of intestinal flora and blood metabolites, patient background information, and dietary questionnaire results	—

Countries

Japan

Contacts

Public ContactYasuteru Kodama

Ohara Clinic Ohara Clinic

official@ohara-clinic.net03-3324-3077

Outcome results