The relationship between COPD and arteriosclerosis: a prospective study

A comparison of the cardio-ankle vascular index in smokers with normal spirometry and smokers with airflow limitation: a cross-sectional study - A comparison of the cardio-ankle vascular index in smokers with normal spirometry and smokers with airflow limitation: a cross-sectional study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048909

Enrollment

129

Registered

2022-10-01

Start date

2017-08-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The diagnosis of COPD is made according to the COPD Guidelines of the Japanese Respiratory Society, based on a history of smoking of 10 pack-years or more, evidence of irreversible airflow obstruction, and exclusion of other chronic respiratory diseases. Volunteers aged 60 years and older will be included if they have no abnormal respiratory function on spirometry and have no history of smoking (never smoker, NS) or if they have a history of smoking for more than 10 pack-years but no abnormal spirometry (current or past smoker, CS or PS).

Exclusion criteria

Exclusion criteria: The subjects with COPD exacerbations and/or respiratory infection within 2 months, severe cardiac arrhythmia, heart failure, and severe systemic diseases such as inability to perform spirometry and measurement of CAVI were excluded.

Design outcomes

Primary

Measure	Time frame
CAVI(cardio-ankle vascular index) FEV1(forced expiratory volume in 1 second) FVC(forced vital capacity, forced expiratory volume in 1 second) FEV1/FVC	—

Countries

Japan

Contacts

Public ContactKawachi Shohei

Nagoya University Department of Integrated Health Sciences Nagoya University Graduate School of Medicine

kawachi@met.nagoya-u.ac.jp052-719-1365

Outcome results