Axillary evaluation with targeted axillary dissection using ultrasound visible clips after neoadjuvant chemotherapy for patients with node-positive breast cancer

Axillary evaluation with targeted axillary dissection using ultrasound visible clips after neoadjuvant chemotherapy for patients with node-positive breast cancer - Axillary evaluation with targeted axillary dissection

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048884

Enrollment

Registered

2022-09-08

Start date

2017-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

After a clip is placed in the biopsy-proven node under US guidance, neoadujuvant chematherapy is performed. At the time of surgery, clipped node is removed followed by sentinel lymph node biopsy.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with clinical T1-3, N1,2, M0 breast cancer undergoing NAC followed by surgery.

Exclusion criteria

Exclusion criteria: Patients with internal mammary lymph node metastasis, prior axillary surgery, or pregnancy

Design outcomes

Primary

Measure	Time frame
False negative rate of the targeted axillary dissection is assessed	—

Secondary

Measure	Time frame
Ultrasound identification rate and success removal rate of the clipped node using several localization technique such as fluorescence technique, wire localization, dye injection method, or combination of these techniques under US guidance are assessed	—

Countries

Japan

Contacts

Public ContactHiroe Sugane

Kameda Medical Center Breast Center

sugane.hiroe@kameda.jp0470-92-2211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026