Predictors of heart failure with preserved ejection fraction in patients with diabetes mellitus: exercise stress echocardiographic study

Predictors of heart failure with preserved ejection fraction in patients with diabetes mellitus: exercise stress echocardiographic study - Koto-DM Heart study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048843

Enrollment

200

Registered

2022-10-01

Start date

2023-02-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus

Interventions

Patients are performed exercise stress echocardiography. Echocardiographic parameters during exercise are analyzed.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with preserved left ventricular ejection fraction who are treated for diabetes mellitus more than three months and kept in steady states.

Exclusion criteria

Exclusion criteria: Patients with history of ischemic heart disease within six months Patients with more than moderate degree of valvular disease Patients who are treated for chronic obstructive pulmonary disease Patients with Chronic kidney disease Patients with liver disease Patients with active malignancy

Design outcomes

Primary

Measure	Time frame
The occurrence of heart failure	—

Secondary

Measure	Time frame
Cardiovascular death. The occurrence of atrial fibrillation.	—

Countries

Japan

Contacts

Public ContactMichiyo Yamano

Kyoto Prefectural University of Medicine Cardiovascular Medicine

m-kuro@koto.kpu-m.ac.jp+81-75-251-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026