Postoperative pain
Conditions
Interventions
Intervention is performed during general anesthesia
in the N2O group, general anesthesia is maintained with 60% N2O and 40% FIO2 after tracheal intubation. N2O administration will be terminated immediately after the end of surgery.
Intervention is perf
Sponsors
Keiyu Orthopedic Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 20 years or older with ASA (American Society of Anesthesiologist) classification I-II who will undergo lumbar spinal fusion between September 2022 and April 2024 at Keiyu Orthopaedic Hospital will be included.
Exclusion criteria
Exclusion criteria: Due to trauma (fracture, nerve damage), not speaking Japanese, impaired consciousness (if difficult to assess). Complications of psychiatric disorders, history of blood disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| low back pain and lower limb pain intensity (Numerical Rating Scale (NRS): 0-10) up to 48 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Postoperative numbness in the lower limb (numbness score: 0-3) (2) Dose of fentanyl by iv-PCA (3) Number of times of administration of adjuvant analgesics (4) Number of points of nausea and vomiting (5) Relationship between time to surgery and pain | — |
Countries
Japan
Contacts
Public ContactNao Fujita
Keiyu Orthopedic Hospital Director of a hospital
Outcome results
None listed