The therapeutic effect of oral Semaglutide in older patients with type 2 diabetes mellitus

The therapeutic effect of Oral Semaglutide in older patients with type 2 diabetes mellitus; retrospective study. - Effect of oral Semaglutide in older patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048782

Enrollment

Registered

2022-08-29

Start date

2022-05-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are 65-year-old or older 2) Patients with HbA1c of 7.0% or higher 3) Patients who do not refuse to participate in this study

Exclusion criteria

Exclusion criteria: 1) Patients with a history of hypersensitivity to the components of semaglutide 2) Patients with severe ketosis, diabetic coma or pre-coma 3) Other patients deemed to be unsuitable by the investigator

Design outcomes

Primary

Measure	Time frame
The change from baseline in HbA1c after 6 months of treatment	—

Secondary

Measure	Time frame
1) The change of various parameters in blood and urine tests (liver, kidney, lipid, etc.) 2) The changes of weight, abdominal circumference, blood pressure, and pulse rate. 3) Adverse events during observation period 4) Factors contributed to changes in HbA1c and secondary endpoints 5) The change of each factor when the degree of dementia is stratified by the simple cognitive function tests 6) Association between scores of simple cognitive function tests and the change of HbA1c	—

Measure

Time frame

1) The change of various parameters in blood and urine tests (liver, kidney, lipid, etc.) 2) The changes of weight, abdominal circumference, blood pressure, and pulse rate. 3) Adverse events during observation period 4) Factors contributed to changes in HbA1c and secondary endpoints 5) The change of each factor when the degree of dementia is stratified by the simple cognitive function tests 6) Association between scores of simple cognitive function tests and the change of HbA1c

—

Countries

Japan

Contacts

Public ContactYuki Oe

Hokkaido University Graduate School Department of Rheumatology, Endocrinology and Nephrology

o-e.yuki@med.hokudai.ac.jp011-706-5915

Outcome results