Pathophysiological analysis of diarrhea in critically ill patients

Pathophysiological analysis of disruption of intestinal homeostasis and diarrhea in critically ill patients - Pathophysiological analysis of disruption of intestinal homeostasis and diarrhea in critically ill patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048779

Enrollment

100

Registered

2022-08-29

Start date

2022-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critically ill patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients expected to require intensive care for more than 48 hours

Exclusion criteria

Exclusion criteria: Patients with inflammatory bowel disease Patients with diarrhea prior to ICU admission Patients who have received multiple antimicrobial agents for a long period of time prior to ICU admission Patients who are judged by the principal investigator to be inappropriate as study subjects

Design outcomes

Primary

Measure	Time frame
Changes in dysbiosis of intestinal microbiota, stool protein concentration, and metabolite concentration in patients with diarrhea.	—

Countries

Japan

Contacts

Public ContactTakehiko Oami

Chiba University Hospital Emergency and Critical Care Medicine

seveneleven711thanks39@msn.com4042227171

Outcome results