Metagenome analysis of microbiota in patients with severe motor and intellectual disabilities and intervention of bifidobacterium

Metagenome analysis of microbiota in patients with severe motor and intellectual disabilities and intervention of bifidobacterium - Intervention of bifidobacterium in SMIDs

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048762

Enrollment

Registered

2022-09-01

Start date

2021-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe motor and intellectual disabilities

Interventions

intervention period: 8 weeks dosage: bifidobacterium BB536 2g/day intervention: once a day intervention period: 8 weeks dosage: lactulose 10g/day intervention: once a day intervention period:

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)patients with severe motor and intellectual disabilities 2)tube feeding

Exclusion criteria

Exclusion criteria: usage of anti-biotics

Design outcomes

Primary

Measure	Time frame
Metagenome analysis of microbiota before and after 4 weeks and 8 weeks during treatment, and after 4 weeks of cessation	—

Countries

Japan

Contacts

Public ContactNaoyuki Tanuma

Tokyo Metropolitan Fuchu Medical Center for the Disabled Department of Pediatrics

Naoyuki_Tanuma@member.metro.tokyo.jp042-323-5115

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026