Comparison of microembolic signals on carotid artery Doppler ultrasound between high power and low power setting during radiofrequency catheter ablation for atrial fibrillation

Comparison of microembolic signals on carotid artery Doppler ultrasound between high power and low power setting during radiofrequency catheter ablation for atrial fibrillation - Comparison of microembolic signals on carotid artery Doppler ultrasound between high power and low power setting during radiofrequency catheter ablation for atrial fibrillation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048658

Enrollment

Registered

2022-08-12

Start date

2022-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation

Interventions

High power short duration ablation Low power long duration ablation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for radiofrequency catheter ablation of AF Required ablation for pulmonary vein isolation and tricuspidisthmus ablation only Adequate evaluation on carotid artery Doppler ultrasound Stable condition with sufficient collection of the coagulation marker preoperatively Therapeutic range of the PT-INR in patients taking warfarin

Exclusion criteria

Exclusion criteria: Required additional extensive ablation in left atrium Hematologic disease and those patients with chemotherapy A history of major surgery and active inflammatory disease within 1 month Antiplatelet drug administration Severe atherosclerosis in aorta and carotid artery Inapplicable to include the study by an attending doctor

Design outcomes

Primary

Measure	Time frame
The number of microembolic signals and microbubble signals	—

Secondary

Measure	Time frame
Size of microembolic signals, changes in coagulation markers, clinical embolic events, MMSE score	—

Countries

Japan

Contacts

Public ContactSatoshi Yanagisawa

Nagoya University Graduate School of Medicine Department of Advanced Cardiovascular Therapeutics

yanagisawa-sato@med.nagoya-u.ac.jp81527442148

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026