Type 2 diabetes
Conditions
Interventions
None listed
Sponsors
Hokkaido University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with type 2 diabetes who were hospitalized in Hokkaido University Hospital from August 2020 to December 2020. 2) 20-90 years old 3) Patients who have been treated with metformin 500-1,000 mg/day with appropriate dietary therapy 4) Treatment with imeglimin or metformin dose escalation will be appropriate to achieve preferable glycemic control 5) Patients who will receive CGM assessment 6) Agreement to participate to this study
Exclusion criteria
Exclusion criteria: 1) History of anaphylaxis of imeglimin or metformin 2) Unstable diabetic retinopathy 3) Severe hepatic dysfunction, renal dysfunction(eGFR<45 mL/min/1.73m2) 4) Pregnancy 5) Diabetic ketosis, coma and precoma 6) Serious infection, pre-or post-surgery 7) Poor adherence to dietary therapy 8) Poor insulin secretion 9) Patients who thought to be inappropriate to enter this study for some reasons by physician's judgments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of indices for glycemic variability before and after changing the treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Influencing factors on changes of CGM parameters | — |
Countries
Japan
Contacts
Public ContactHiroshi Nomoto
Hokkaido University Hospital Department of diabetology and endocrinology
Outcome results
None listed