None
Conditions
Interventions
None listed
Sponsors
Shiseido Co., ltd.
KAGOME CO., LTD
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. healthy women 2. Aged 30 to 44 years 3. Regular menstrual cycle between 25-38 days 4. The blood sampling date does not correspond to the ovulation period, and the skin measurement date does not correspond to the luteal phase * As much as possible 5. Outdoor activity time less than 20 hours per week 6. Daily rhythm of waking up in the morning and going to bed at night (excluding night shifts and two shifts) 7. Daily sleep time of 5 hours or more continuously 8. Individuals who agree to participate in the study
Exclusion criteria
Exclusion criteria: 1. Individuals with hay fever 2. Individuals with significant abnormalities in the measurement site 3. Individuals with chronic skin symptoms such as atopic dermatitis at the measurement site 4. Individuals who have undergone treatments that affect the measurement site (stain removal laser, chemical peeling, iontophoresis, etc.) within the past 2 months 5. Individuals who go to the hospital and are using medicines (including taking low-dose pills) 6. Individuals who have participated in other studies within the last 2 months 7. Individuals who are currently taking medicines, foods for specified health uses, foods with nutrition claims, foods with functional claims, and so-called health foods (including beauty supplements) on a daily basis. 8. Individuals who routinely consume nutritionally functional foods intended to supplement vitamins and minerals 9. Individuals who have been using whitening cosmetics (tranexamic acid, hydroquinone-containing quasi-drugs, etc.) in the last 3 months 10. Individuals who have used cosmetics (peeling gel, scrubbed face wash, etc.) for exfoliating the measurement site in the past 3 months 11. Individuals who consume excessive alcohol 12. Smoker 13. Individuals whose lifestyle may change from one week before the exam to the day before the exam (night shift, long trip, etc.) 14. Asthma patients 15. Individuals with symptoms of insomnia 16. Pregnant or planned or lactating individuals 17. Infant parenting individuals 18. Individuals with a BMI of less than 18.5 or a BMI of 25 or higher 19. In addition, individuals (non-cooperative subjects, etc.) who are judged to be inappropriate by the person in charge of the examination or the person in charge of the examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss Skin color Intake of green and yellow vegetables Dermal carotenoid levels Serum carotenoid concentrations | — |
Secondary
| Measure | Time frame |
|---|---|
| Moisture content of the stratum corneum State of the stratum corneum AGEs Full face photo Body composition Vital data Autonomic nerves Dietary survey questionnaire Blood factors Urinary factors | — |
Countries
Japan
Contacts
Public Contactmiho miyanaga
Shiseido Co., ltd. Frontier Business R&D
Outcome results
None listed