Evaluation of the physiological change in knee articular structures using quantitative MRI analysis

Evaluation of the physiological change in knee articular structures with T1rho/T2 mapping: the difference between before and after the exercise, and the diurnal change - KAS-T1rho/T2 mapping

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048586

Enrollment

Registered

2022-08-10

Start date

2022-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

1. Healthy subjects are asked to do exercises (jump rope 20 times x 10 sets, repetitive side jump 20 seconds x 10 sets, bending and stretching exercise 10 times x 10 sets) and bed rest, and a knee joi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Men and women aged 20 to 30 with written informed consent

Exclusion criteria

Exclusion criteria: 1. People who have a history of knee joint injury, treatment, or surgery, or patients who have been pointed out to have some kind of abnormality. 2. Cases with some symptoms in the knee joint. 3. Cases where sports or exercise is prohibited or cannot be done for some reason, or for some reason, standing, sitting, or lying down is prohibited or impossible. 4. Cases corresponding to MRI contraindication. 5. Cases in which MRI artifacts are likely to appear and signal values are difficult to measure. 6. History of malignant tumor 7. Those who may be pregnant

Design outcomes

Primary

Measure	Time frame
Knee joint MRI (T1rho mapping, T2 mapping)	—

Countries

Japan

Contacts

Public ContactKeita Nagawa

Saitama medical university Radiology department

radmini@saitama-med.ac.jp049-276-1265

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026