Studies on the relationship between antibody titer due to vaccination with novel coronavirus vaccine, and blood PBMC activity and dietary habits

Studies on the relationship between antibody titer due to vaccination with novel coronavirus vaccine, and blood PBMC activity and dietary habits - Studies on the relationship between antibody titer due to vaccination with novel coronavirus vaccine, and blood PBMC activity and dietary habits

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048537

Enrollment

300

Registered

2022-08-01

Start date

2022-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy male/female adults

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Persons who are participating in the "Kanagawa ME-BYO Cohort Study" and have valid responses to the questionnaire regarding the frequency of yogurt consumption. (2) Persons who are participating in the "Citywide monitoring of COVID-19 using the genome cohort" and have been tested for SARS-CoV-2 infection. (3) Persons who have been fully informed about the study, are able to understand its contents, and are able to give their written consent.

Exclusion criteria

Exclusion criteria: (1) Persons with a history or current history of autoimmune or other immune-related diseases (2) Persons who are pregnant (3) Persons who have contracted an infectious disease during the period from 30 days prior to the date of obtaining consent (4) Persons who have donated 200 mL of blood in one month before start of the study (5) Males who have donated 400 mL of blood within 3 months before start of the study (6) Females who have donated 400 mL of blood within 4 months before start of the study (7) Males whose blood collected in the 12 months before study plus the expected blood for the study exceeds 1200 mL (8) Females whose blood collected in the 12 months before study plus the expected blood for the study exceeds 800 mL (9) Persons who are judged by the investigator or sub-investigator to be inappropriate to participate in this study

Design outcomes

Primary

Measure	Time frame
Relationship between PBMC activity and the results of SARS-CoV-2 infection test	—

Secondary

Measure	Time frame
- Relationship between PBMC activity and frequency of yogurt intake - Relationship between PBMC activity and intestinal microbiota - Relationship between frequency of yogurt intake and intestinal microbiota - Relationship between frequency of yogurt intake and the results of SARS-CoV-2 infection test - Relationship between the intestinal microbiota and the results of SARS-CoV-2 infection test - Relationship between the trend of SARS-CoV-2 infection test results and the trend of PBMC activity - Relationship between the trend of SARS-CoV-2 infection test results and intestinal microbiota	—

Measure

Time frame

- Relationship between PBMC activity and frequency of yogurt intake - Relationship between PBMC activity and intestinal microbiota - Relationship between frequency of yogurt intake and intestinal microbiota - Relationship between frequency of yogurt intake and the results of SARS-CoV-2 infection test - Relationship between the intestinal microbiota and the results of SARS-CoV-2 infection test - Relationship between the trend of SARS-CoV-2 infection test results and the trend of PBMC activity - Relationship between the trend of SARS-CoV-2 infection test results and intestinal microbiota

—

Countries

Japan

Contacts

Public ContactHiroshi Kano

Meiji Co., Ltd. Basic Microbiology Research Department Food Microbiology and Function Research Laboratories R&D Div.

none@none+81-42-632-5838

Outcome results