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Exploratory study on the evaluation of sound saliency using pupil diameter as an indicator and its potential clinical application

Exploratory study on the evaluation of sound saliency using pupil diameter as an indicator and its potential clinical application - Exploratory study on the evaluation of sound saliency using pupil diameter as an indicator

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000048529
Enrollment
80
Registered
2022-08-01
Start date
2022-07-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus, Hyperacusis

Interventions

None listed

Sponsors

Tohoku University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (A) Healthy hearing subjects (1) Healthy hearing subjects with no history of ear disease or neurological/neurological disease 2) Age: 20 years old or older, less than 40 years old (at the time of registration) (3) Gender: Any gender (B) Tinnitus patients (1) Patients with a tinnitus severity score (Tinnitus Handicap Inventory: THI) of 40 points or higher (THI is a tinnitus severity questionnaire routinely administered in the outpatient clinic (maximum score 100 points); a score of 40 or more is considered to indicate moderate or severe tinnitus requiring some form of therapeutic intervention.) (2) Age: 20 years old or older, less than 40 years old (3) Gender: Any gender. (C) Hyperacusis patients (1) Patients with a hearing sensitivity score (Hyperacusis Questionaire: HQ) of 28 points or higher (HQ is a questionnaire on the degree of distress of auditory sensitivity that is routinely administered in the outpatient clinic (maximum score 42 points). 28 points or more is considered as having a strong auditory sensitivity that requires some therapeutic intervention.) (2) Age: 20 years old or older, less than 40 years old (iii) Gender: Any gender.

Exclusion criteria

Exclusion criteria: (A) Hearing subjects 1) Those with a history of ear disease 2) Those with a history of mental illness 3) Those with a history of peripheral or central nervous system diseases 4) Those with a history of eye diseases (excluding myopia) 5) Those who are taking drugs that may affect the pupil system (antihistamines, decongestants, antidepressants, anti-vomiting agents, anticonvulsants, Parkinson drugs, etc.) 6) Those who are pregnant or may become pregnant 7) In addition, those who are judged by the principal investigator or coordinator to be inappropriate as subjects (B) Tinnitus patients, hyperacusis patients 1) Those with a history of eye diseases (excluding myopia) 2) Those who are taking drugs that may affect the pupil system (antihistamines, decongestants, antidepressants, anti-vomiting agents, anticonvulsants, Parkinson drugs, etc.) 3) Those who are pregnant or may become pregnant 4) In addition, those who are judged by the principal investigator or coordinator to be inappropriate as subjects

Design outcomes

Primary

MeasureTime frame
pupil diameter

Countries

Japan

Contacts

Public ContactTetsuaki Kawase

Tohoku University Graduate School of Biomedical Engineering

kawase@orl.med.tohoku.ac.jp022-717-7303

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026