Effect of gait training using Welwalk and Botulinum Toxin A Injection on gait ability in chronic stroke patients

Effect of gait training using Welwalk and Botulinum Toxin A Injection on gait ability in chronic stroke patients - Combined effects of gait training using Welwalk and Botulinum Toxin A Injection in chronic stroke patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048477

Enrollment

Registered

2022-07-27

Start date

2022-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic stroke patients

Interventions

Gait exercise using Welwalk after botulinum toxin type A therapy (40 min/day, 5 days/week for 4 weeks) Botulinum Toxin A Injection alone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.>6 months duration after stroke 2.Hemiparesis and spasticity due to ischemic or hemorrhage on the unilateral tent (lower extremity modified Ashworth Scale of more than 1+) 3.Independent in ground ambulation with or without the use of a unilateral assistive device (standard cane, four-pronged cane) and with or without the use of a an ankle foot orthoses. 4.Independent in treadmil gait training 5.Approval for study participation

Exclusion criteria

Exclusion criteria: 1.Cannot obey instructions of a healer (scores < 23 on the Mini Mental Status examination, etc) 2.Significant cardiorespiratory/metabolic disease, or orthopedic injury or other neurological 3.Excessive spasticity (defined as modified Ashworth scale 4 at any lower limb joint) 4.Size limitations for the harness/counterweight system or robotic orthosis 5.Receiving anti-spasticity therapy (Botulinum Toxin A, phenol, baclofen pump, etc.) in the lower extremities within 16 weeks of study entry

Design outcomes

Primary

Measure	Time frame
Gait analysis	—

Secondary

Measure	Time frame
Range of motion (knee, ankle) Modified Ashworth Scale (MAS) 10m gait velocity 6-minute walk distance Timed up to Go Global rating of change scale MOS Physical Cost Index8-Item Short-Form Health Survey Physical Cost Index Physical activity electromyogram of the lower limb	—

Countries

Japan

Contacts

Public ContactTomoyuki Ogino

Hyogo medical university School of Rehabilitation

to-ogino@hyo-med.ac.jp078-304-3184

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026