A multi center, phase 3 study to evaluate safety and efficacy of extensive intraoperative peritoneal lavage, that project to prevent recurrence, in the laparoscopic surgery for advanced colon cancer

A multi center, phase 3 study to evaluate safety and efficacy of extensive intraoperative peritoneal lavage, that project to prevent recurrence, in the laparoscopic surgery for advanced colon cancer - SENJYO study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048457

Enrollment

2600

Registered

2022-07-26

Start date

2022-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

locally advanced colon cancer

Interventions

In the treatment group, surgeons perform EIPL (extensive intraoperative peritoneal lavage). In the control group, surgeons perform peritonel lavage with less than 1L of saline.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Written consent to participate in the study has been obtained from the patient. 2) Performance Status (ECOG) of either 0 or 1. 3) Patient has operable general condition and organ function. 4) Patients with scheduled laparoscopic surgery for locally advanced colon cancer.

Exclusion criteria

Exclusion criteria: 1) Patients with history of surgery within 4weeks 2) Patients with multiple cancers

Design outcomes

Primary

Measure	Time frame
Relapse free survival of pathological T4 and/or N2 cases	—

Countries

Japan

Contacts

Public ContactYusuke Takahashi

National Hospital Organization Osaka National Hospital Department of Surgery

takahashi.yusuke.eu@mail.hosp.go.jp06-6942-1331

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026