Pathophysiology of bronchopulmonary dysplasia focusing on the IL-33 pathway

Pathophysiology of bronchopulmonary dysplasia focusing on the IL-33 pathway - Pathophysiology of bronchopulmonary dysplasia focusing on the IL-33 pathway

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048420

Enrollment

110

Registered

2022-08-01

Start date

2022-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary dysplasia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Preterm infants born at less than 30 weeks gestation requiring ventilatory support such as ventilatory mechanical ventilation, continuous positive airway pressure, high flow nasal cannula etc.

Exclusion criteria

Exclusion criteria: congenital multiple malformation syndrome, chromosome abnormalities, congenital airway malformations

Design outcomes

Primary

Measure	Time frame
Serum IL-33 concentration at corrected 36 weeks	—

Secondary

Measure	Time frame
IL-33 pathway IL-4, IL-5, IL-13, TSLP at corrected 36 weeks; IL-6, IL-8, VEGF, TNF-alpha and other cytokines in the acute phase.	—

Countries

Japan

Contacts

Public ContactKenichi Suga

Tokushima University Hospital Department of pediatrics

suga.kenichi.1@tokushima-u.ac.jp+81-88-633-7135

Outcome results