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Study on estimation of light response of biological clock

Exploratory research for simple measurements indexs and estimation formulas that can estimate light reponse of human biological clock - Exploratory research for simple measurements indexs and estimation formulas that can estimate light reponse of human biological clock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000048408
Enrollment
30
Registered
2022-08-31
Start date
2022-09-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Behavior control 5 hours light exposure

Sponsors

National Center of Neurology and Psychiatry
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Males between 20 and 35 years of age

Exclusion criteria

Exclusion criteria: 1. Volunteers who are taking or have a history of a pre-existing medical disease (cardiovascular, liver, endocrine, brain/neurological, psychiatric, etc.) or therapeutic medication that may affect results of the study. 2. Volunteers with abnormal color vision. 3. Volunteers who have engaged in jet lag travel or shift work at least six months prior to the experiment. 4. Volunteers who are dependent on alcohol or have excessive drinking habits. 5. Volunteers who have and excessive smoking habits. 6. Volunteers who have habits of taking drugs or supplements that affect sleep. 7. Other persons determined to be inappropriate by the principal investigator.

Design outcomes

Primary

MeasureTime frame
Discovery of indexes associated with the degree of melatonin suppression (light responsiveness of the biological clock)

Secondary

MeasureTime frame
Constraction of a formula for estimating the degree of melatonin suppression. Dose-response relationship between melatonin suppression and illuminance in Japanese.

Countries

Japan

Contacts

Public ContactTaisuke Eto

National Center of Neurology and Psychiatry Department of Sleep-Wake Disorders, National Institute of Mental Health

eto@ncnp.go.jp042-346-2071

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026