X1 study

Dual-focus versus conventional magnification endoscopy with narrow-band imaging for the optical diagnosis in Large Colorectal Polyps: an image-based pilot study - X1-JNET study 1

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048393

Enrollment

350

Registered

2022-07-31

Start date

2022-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon polyp

Interventions

Endoscopic magnified observation with NBI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cases undergo colonoscopy using the X-1 endoscopy system and new endoscopies (CF-XZ1200I or CF-EZ1500DI) at Shizuoka Cancer Center, Sano Hospital, and Kyoto Second Red Cross Hospital

Exclusion criteria

Exclusion criteria: 1. Cases with inflammatory bowel disease or with polyposis syndrome 2. Cases with blood coagulation dysfunction or with unavailable suspension of anticoagulants 3. Cases deemed unsuitable as a subject in the study by the investigator for some other reason

Design outcomes

Primary

Measure	Time frame
The sensitivity for pT1b cancer in Dual-Focus and Full-Zoom magnified NBI endoscopy	—

Secondary

Measure	Time frame
The concordance between the histology and magnified NBI findings according to Japan NBI expert Team (JNET) cllasification	—

Countries

Japan

Contacts

Public ContactKenichiro Imai

Shizuoka Cancer Center Division of Endoscopy

ke.imai@scchr.jp055-989-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026