Prediction of postoperative complications in digestive organ cancer by cell free DNA measurement

Prediction of postoperative complications in digestive organ cancer by cell free DNA measurement - Prediction of postoperative complications in digestive organ cancer by cell free DNA measurement

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048372

Enrollment

1000

Registered

2022-08-01

Start date

2022-06-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive organ cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with digestive organ cancer or precancerous lesion requiring standard therapy. 2. 20 years and more at informed consent. 3. Ability to understand and the willingness to sign a written informed consent document.

Exclusion criteria

Exclusion criteria: 1. Patients whose consent cannot be obtained. 2. Patients whose participation in the trial was judged to be inappropriate by the attending doctor.

Design outcomes

Primary

Measure	Time frame
Association of perioperative cell free DNA amount and fragment length with postoperative complications.	—

Secondary

Measure	Time frame
1. Association of perioperative cell free DNA amount and fragment length with clinicopathological factors. 2. Association of perioperative cell free DNA amount and fragment length with operative procedure. 3. Association of perioperative cell free DNA amount and fragment length with recurrence and prognosis. 4. Association of perioperative cell free DNA amount and fragment length with frailty in patients older than 65 years.	—

Measure

Time frame

1. Association of perioperative cell free DNA amount and fragment length with clinicopathological factors. 2. Association of perioperative cell free DNA amount and fragment length with operative procedure. 3. Association of perioperative cell free DNA amount and fragment length with recurrence and prognosis. 4. Association of perioperative cell free DNA amount and fragment length with frailty in patients older than 65 years.

—

Countries

Japan

Contacts

Public ContactYuki Nakamura

Wakayama Medical University Second Department of Surgery

y-nakamu@wakayama-med.ac.jp073-441-0613

Outcome results