Prospective observational study on changes in the microbial flora of the oral cavity following head and neck radiotherapy for the establishment of oral hygiene management.

Prospective observational study on changes in the microbial flora of the oral cavity following head and neck radiotherapy for the establishment of oral hygiene management. - The microbial flora and head and neck radiotherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048332

Enrollment

Registered

2022-07-12

Start date

2022-07-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Age between 20 and 80 (2) ECOG PS 0-2 (3) Head and neck cancer patients (nasopharyngeal cancer, oropharyngeal cancer, hypopharyngeal cancer, nasal/paranasal cavity cancer, laryngeal cancer, salivary gland cancer) who will receive primary radiation therapy. (4) Informed consent is obtained from the patients.

Exclusion criteria

Exclusion criteria: (1) Patients with active bacterial or fungal infection in the oral cavity. (2) Patients with a mental impairment who has not the ability to participate in the clinical study. (3) Patients whom the attending physician deemed not appropriate to participate in the clinical trial.

Design outcomes

Primary

Measure	Time frame
To investigate the relationship between the type of specific bacterias and the severity of radiation-induced acute mucositi.	—

Countries

Japan

Contacts

Public ContactNaoya Murakami

National Cancer Center Hospital Department of Radiation Oncology

ore.murakami@gmail.com+81-33542-2511

Outcome results