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The role of magnesium on catechol-o-methyltransferase in preeclampsia

The role of magnesium on catechol-o-methyltransferase in preeclampsia - The role of magnesium on catechol-o-methyltransferase in preeclampsia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000048269
Enrollment
200
Registered
2022-07-04
Start date
2021-03-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclampsia

Interventions

blood sampling

Sponsors

Juntendo University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: i) Patients aged 16 years or older at the time of obtaining consent. 2) Patients diagnosed with preeclampsia or hypertensive disorders of pregnancy. (iii) Patients who undergo antenatal checkups and delivery at Juntendo Hospital. (iv) Patients who have received a full explanation of their participation in this study, and who have given written consent of their own free will based on a full understanding of the study.

Exclusion criteria

Exclusion criteria: (1) Patients with a history of known genetic disorders. (ii) Patients receiving treatment due to other complications or pre-existing conditions. (iii) Other patients deemed unsuitable as subjects by the principal investigator.

Design outcomes

Primary

MeasureTime frame
the level of magnesium and 2-methoxyestradiol in serum and cord blood

Secondary

MeasureTime frame
the level of magnesium in placenta and COMT activity

Countries

Japan

Contacts

Public ContactNorikazu Ueki

Jutendo University department of obstetrics and gynaecology

n-ueki@juntendo.ac.jp0358021100

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026