Epidemiological studies on the relationship between age, sensorineural hearing loss, and the distribution of blood NAD+ levels

Epidemiological studies on the relationship between age, sensorineural hearing loss, and the distribution of blood NAD+ levels - Epidemiological studies on the relationship between age, sensorineural hearing loss, and the distribution of blood NAD+ levels

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000048229

Enrollment

Registered

2022-07-02

Start date

2022-07-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sensorineural hearing loss

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Healthy person without hearing loss in 50s (2) Patients in 50s with sudden hearing loss (unilateral severe) 3) Patients in 80 years of age and older with bilateral severe or profound hearing loss 4) Patients in 80 years of age and older with no bilateral severe or profound hearing loss 5) Patients who can abstain from food in the morning and can visit the clinic in the morning. (6) Patients who give consent to participate in the study.

Exclusion criteria

Exclusion criteria: (1) Patients with hearing loss due to factors unrelated to aging, such as trauma or hearing loss due to complications from other diseases (2) Patients taking nicotinamide mononucleotide (NMN)

Design outcomes

Primary

Measure	Time frame
Blood NAD+ levels in healthy subjects without hearing loss in 50s, in patients with sudden hearing loss (unilateral severe) in 50s, in patients with bilateral severe and advanced hearing loss in 80 years of age and older, and in patients without bilateral severe and advanced hearing loss in 80 years of age and older.	—

Countries

Japan

Contacts

Public ContactHideaki Sakata

Kawagoe Otology Institute Division of Otorhinolaryngology

sakata@jikagaku.jp049-226-3387

Outcome results