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Verification of the effect of sacubitril valsartan sodium hydrate on the residual renal function of peritoneal dialysis patients

Verification of the effect of sacubitril valsartan sodium hydrate on the residual renal function of peritoneal dialysis patients - Verification of the effect of sacubitril valsartan sodium hydrate on the residual renal function of peritoneal dialysis patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000048227
Enrollment
45
Registered
2022-07-01
Start date
2022-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal failure

Interventions

Test group: Sacubitril valsartan sodium hydrate use group. ARB group: RAS inhibitor use group. Control group: Sacubitril valsartan sodium hydrate and no RAS inhibitor.

Sponsors

International University of Health and Welfare
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: This study targets peritoneal patients who are visiting the International University of Health and Welfare Hospital, the International University of Health and Welfare Narita Hospital, and the Keio University Hospital, and who have consented to participate in the study.Patients should be less than 3 months after the introduction of peritoneal dialysis.

Exclusion criteria

Exclusion criteria: Those who did not consent to participate in the study.

Design outcomes

Primary

MeasureTime frame
Comparison of the rate of decrease in residual renal function in each group after 6 months of distribution to 3 groups.

Secondary

MeasureTime frame
Comparison of blood pressure in each group after 6 months of distribution to 3 groups .Comparison of cardiac function (EF) by Biplane Modified Simpson method in each group after 6 months of 3 groups.Comparison of peritoneal function in each group after 6 months of distribution to 3 groups.

Countries

Japan

Contacts

Public ContactKazuya Sugita

International University of Health and Welfare Kidney Internal Medicine Course

ksugita0425@yahoo.co.jp08031522251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026