esophageal cancer
Conditions
Interventions
One sachet of bifidobacterium powder is administered in the evening of the first postoperative day. From the second to the seventh postoperative day, One sachet of bifidobacterium powder is administer
Sponsors
Nagoya City University Graduate School of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with stage 2 and 3 esophageal cancer who are scheduled to undergo esophagectomy. 2) Patients who are scheduled to start enteral nutrition according to the clinical pathway of this hospital after surgery. 3) Patients with or without preoperative chemotherapy 4) Patients with or without multiple cancers 5) Patients 20 years of age or older 6) Patients who can obtain informed consent from the patient
Exclusion criteria
Exclusion criteria: 1) Patients with Performance Status of 3 or higher 2) Patients with serious complications such as poorly controlled diabetes mellitus or hypertension 3) Patients with muscle diseases including active myopathy or muscular dystrophy 4) Patients who are pregnant or lactating 5) Patients who participated in clinical trial or clinical research involving the use of an unapproved drug and received an investigational drug or unapproved drug at least 16 weeks prior to the informed consent 6) Patients who are determined to be ineligible for this study by the principal investigator or subinvestigator 7) Patients who are allergic to the study food 8) Patients who failed to obtain informed consent or withdrew informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| abundance of proteobacteria in feces | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Species and diversity score of gut microbiota 2) Gastrointestinal symptoms after surgery 3) Frequency and severity of infectious complications 4) Frequency and severity of other postoperative complications 5) Length of hospital stay after surgery 6) Nutritional intake 7) Blood test | — |
Countries
Japan
Contacts
Public ContactRyo Ogawa
Nagoya City University Graduate School of Medical Sciences Gastroenterological Surgery
Outcome results
None listed