Effect of individualized blood pressure management on postoperative outcomes in hypertensive patients undergoing major surgery

Effect of individualized blood pressure management on postoperative outcomes in hypertensive patients undergoing major surgery - Effect of individualized blood pressure management on postoperative outcomes in hypertensive patients undergoing major surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048163

Enrollment

400

Registered

2022-06-25

Start date

2022-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive patients undergoing major surgery

Interventions

Intraoperative individualized blood pressure management to maintain mean blood pressure within 10% of the reference value Intraoperative blood pressure management to maintain mean blood pressure 65mmH

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Hypertensive patients undergoing major abdominal surgery

Exclusion criteria

Exclusion criteria: 1. Emergency cases 2. Patients who will receive mechanical ventilation after surgery 3. Preoperative acute kidney injury (preoperative eGFR<30 ml/min/1.73m2) 4. Kidney surgery 5. Surgery requiring hypotensive management 6. Preoperative mean blood pressure less than 75mmHg

Design outcomes

Primary

Measure	Time frame
Incidence of acute kidney injury within 7 days after surgery	—

Secondary

Measure	Time frame
Incidence of AKI (stage >=2) within 7 days after surgery, initiation of renal replacement therapy (RRT) (intermittent hemodialysis or continuous hemodiafiltration) within 7 days after surgery	—

Countries

Japan

Contacts

Public ContactKoichi Suehiro

Osaka Metropolitan University Graduate School of Medicine Department of Anesthesiology

suehirokoichi@yahoo.co.jp0666452186

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026