A verification study of the promoting effect of the test food on vitamin C absorption into the blood

A verification study of the promoting effect of the test food (1000 mg) on vitamin C absorption into the blood: a randomized, placebo-controlled, double-blind, crossover comparison trial - A verification study of the promoting effect of the test food (1000 mg) on vitamin C absorption into the blood

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048161

Enrollment

Registered

2022-06-24

Start date

2022-06-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Japanese subjects

Interventions

Test food: &lt

Period I&gt

Nano tone liposomal vitamin C &lt

Period II&gt

Non-treated vitamin C Administration: Dissolve one packet in water (200 mL) and drink within five minutes *The intervention sequence is Period I to Period II, and each food is single ingestion.

Non-treated vitamin C &lt

Nano tone liposomal vitamin C Administration: Dissolve one packet in water (200 mL) and drink within five minutes *The intervention sequence is Period I to Period II, and each food is single inge

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Japanese 2. Men or women 3. Adults 4. Healthy subjects

Exclusion criteria

Exclusion criteria: 1. Subjects who are undergoing medical treatment or have a medical history of malignant tumor, heart failure, and myocardial infarction 2. Subjects who have a pacemaker or an implantable cardioverter defibrillator (ICD) 3. Subjects who currently undergoing treatment for any of the following chronic disease: cardiac arrhythmia, liver disorder, kidney disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases 4. Subjects who use or take "Foods for Specified Health Uses," or "Foods with Functional Claims" in daily 5. Subjects who currently taking medications (including herbal medicines) and supplements 6. Subjects who are allergic to medicines and/or the test food related products (particularly soy) 7. Subjects who are pregnant, lactation, or planning to become pregnant 8. Subjects who suffer from COVID-19 9. Subjects who have been enrolled in other clinical trials within the last 28 days before the agreement to participate in this trial or plan to participate another trial during this trial 10. Subjects who are judged as ineligible to participate in the study by the physician

Design outcomes

Primary

Measure	Time frame
The maximum blood concentration (Cmax) of vitamin C in the blood	—

Secondary

Measure	Time frame
1. The incremental area under the curve (IAUC), the time to maximum blood concentration (Tmax), and the measured values at each assessment point1 of vitamin C in the blood 1It indicates before test-food consumption, and one, two, three, four, six, and eight hours after test-food consumption	—

Countries

Japan

Contacts

Public ContactNaoko Suzuki

ORTHOMEDICO Inc. R&D Department

nao@orthomedico.jp03-3818-0610

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026