The effect of chronic intake of Dioscorea esculenta powder on menstrual pain in young women

The effect of chronic intake of Dioscorea esculenta powder on menstrual pain in young women-randomized crossover doubleblind study- - The development of new supplement for prevention of severe menstrual pain

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048151

Enrollment

Registered

2022-06-30

Start date

2022-06-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal healthy adult female

Interventions

Participants were administered Dioscorea esculenta (300 mg/day) for 4 weeks during the first trial and, after a 4-week washout period, the Dioscorea esculenta and placebo groups exchanged their assign

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Participants included normal menstruation about 21 days to 35 days as well as has symptoms for PMS and severe menstrual pain

Exclusion criteria

Exclusion criteria: Participants with a history of smoking, medication use, and dietary nutritional supplementation were excluded from this study

Design outcomes

Primary

Measure	Time frame
PGE2, COX-2 MPQ, DRSP	—

Countries

Japan

Contacts

Public ContactKoji Sato

Kobe University Graduate Scholl of Human Development and Environment

sato712@people.kobe-u.ac.jp078-803-7812

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026