Evaluation of peristalsis in the esophageal body using Distension-contraction plot method and esophageal radiography (onigiri esophagography) in healthy volunteers.

Evaluation of peristalsis in the esophageal body using Distension-contraction plot method and esophageal radiography (onigiri esophagography) in healthy volunteers. - Evaluation of peristalsis in the esophageal body using Distension-contraction plot method and esophageal radiography (onigiri esophagography) in healthy volunteers.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048146

Enrollment

Registered

2022-06-23

Start date

2022-06-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteer

Interventions

Esophageal radiography (onigiri esophagography) Requires radiation exposure of about 20 mGy. High-resolution manometry(Distension-contraction plot method) The catheter must be inserted nasally, w

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy volunteers who meet all of the following criteria are eligible. (1) Subjects with no subjective symptoms that would raise suspicion of esophageal motility disorders (2) Subjects who have been confirmed to have normal swallowing function (3) Subjects who fully understand this research protocol and are able to give informed consent (4) Subjects who are between 20 and 65 years old at the time of obtaining consent

Exclusion criteria

Exclusion criteria: Patients are excluded from the study if any one of the following criteria is applicable. (1) Subjects who are taking drugs for improving gastrointestinal motility that may affect esophageal motility within 1 month of the examination (2) Subjects who have undergone upper gastrointestinal surgery (3) Pregnant women or subjects who may become pregnant (4) Subjects who are allergic to Xylocaine or barium (5) Subjects in poor general condition due to severe cardiopulmonary impairment, etc. (6) Subjects who have difficulty understanding the examination protocol or listening to symptoms due to psychological disorders or cognitive impairment. (7) Subjects who have been diagnosed with organic abnormalities such as malignant tumors before registration (8) Subjects with other serious complications that are judged inappropriate by the investigator.

Design outcomes

Primary

Measure	Time frame
Establish the normative thresholds and normal findings for healthy volunteers in the Distension-contraction plot method.	—

Secondary

Measure	Time frame
Relationship between Distension-contraction plot method and esophageal radiography (onigiri esophagography) findings	—

Countries

Japan

Contacts

Public ContactHirotaka Tsuru

Graduate School of Medicine, Kyushu University Department of Medicine and Bioregulatory Science

tsuru.hirotaka.436@m.kyushu-u.ac.jp0926425286

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026