Clinical efficacy of bronchodilator delivery by vibrating mesh nebulizer in mechanical ventilated patients

Clinical efficacy of bronchodilator delivery by vibrating mesh nebulizer in mechanical ventilated patients - Clinical efficacy of bronchodilator delivery by vibrating mesh nebulizer in mechanical ventilated patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048137

Enrollment

Registered

2022-06-23

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients: Spontaneously breathing patients on mechanical ventilation with airway resistance of higher than 6 cmH2O/L/sec measured by PAV+.

Interventions

Delivery of salbutamol 2.5mg by VMN Delivery of salbutamol 0.8mg by MDI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Spontaneously breathing patients (>17 years old) on mechanical ventilation with airway resistance of higher than 6 cmH2O/L/sec measured by proportional assist ventilation (PAV+TM) for whom clinicians decided to administer bronchodilator for appropriate clinical reasons.

Exclusion criteria

Exclusion criteria: -Hypersensitivity to salbutamol -High airway resistance due to endotracheal obstruction

Design outcomes

Primary

Measure	Time frame
Airway resistance and peak expiratory flow measured by PAV+	—

Countries

Japan

Contacts

Public ContactYasuhiro Norisue

Tokyo Bay Urayasu Ichikawa Medical Center Critical care

norisue.yasuhiro@gmail.com0473513101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026