mild cognitive impairment, dementia, and periodontal disease
Conditions
Interventions
None listed
Sponsors
National Center for Geriatrics and Gerontology The Lion Foundation for Dental Health
The Lion Foundation for Dental Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: We enrolled patients visiting the memory clinic at the NCGG who agreed to undergo both medical assessment of their cognitive function and dental examination to survey periodontal disease. Patients were eligible for the study if they: (1) were able to undergo brain MRI; (2) provided informed consent in writing; (3) provided informed consent for the NCGG Biobank to store their clinical data, and blood samples; and (4) were accompanied by a study partner who could assess the condition of the patient.
Exclusion criteria
Exclusion criteria: We excluded patients if they: (1) were unable to undergo MRI examination, or the MRI scan could not be evaluated because of movement; (2) had local lesions, such as cerebral infarction, detected by MRI before enrollment, which could significantly affect cognitive functioning; (3) had a history of a major psychological disorder, or current serious or unstable alcohol or drug abuse; (4) were judged by an investigator to be ineligible to participate as a study subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| periodontal disease, oral, and cognitive functions | — |
Countries
Japan
Contacts
Public ContactKenji Matsushita
National Center for Geriatrics and Gerontology Department of Oral Disease Research, Research Institute
Outcome results
None listed