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Estimation of anti-SARS-CoV-2 effect in saliva from healthy individuals who ingest candies containing tea-derived components

Estimation of anti-SARS-CoV-2 effect in saliva from healthy individuals who ingest candies containing tea-derived components - Anti-SARS-CoV-2 effect in saliva from healthy individuals who ingest candies containing tea-derived components

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000048124
Enrollment
30
Registered
2025-12-31
Start date
2022-07-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Interventions

Ingestion of a candy containing green tea for 5 minutes Ingestion of a candy containing black tea for 5 minutes Ingestion of a candy containing neither green tea nor black tea for 5 minutes

Sponsors

Kyoto Prefectural University of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy volunteers who has no symptoms and do not receive an administration of immunosuppressants including corticosteroid. 2. Patients who voluntarily participate in the study and give written consent. 3. Patients aged 20 years old or above and 75 years old or younger at the time of consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe disease (inducing patients who receive an administration of immunosuppressants including corticosteroid). 2. Patients with history of either liver or kidney disease. 3. Patients allergic for either tea or catechins. 4. Patients whom the doctor in attendance considers inadequate for the study.

Design outcomes

Primary

MeasureTime frame
Viral inactivation effects in saliva before ingestion of a candy containing tea-derived components and 0, 5 and 15 min after cessation of the candy ingestion.

Secondary

MeasureTime frame
Concentrations of catechin-related components in the saliva before ingestion of a candy containing tea-derived components and 0, 5 and 15 min after cessation of the candy ingestion. And viral RNA levels of SARS-CoV-2 treated with the saliva samples.

Countries

Japan

Contacts

Public ContactOsam Mazda

Kyoto Prefectural University of Medicine Department of Immunology

mazda@koto.kpu-m.ac.jp+81-75-251-5330

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026