Effects of a dairy ingredient on subjective symptoms in healthy subjects: a randomized, double-blind, placebo-controlled trial.

Effects of a dairy ingredient on subjective symptoms in healthy subjects: a randomized, double-blind, placebo-controlled trial. - Effects of a dairy ingredient on subjective symptoms in healthy subjects.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048087

Enrollment

160

Registered

2022-06-19

Start date

2022-06-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None (Healthy subjects)

Interventions

Ingestion of dairy ingredient for 12 weeks. Ingestion of placebo for 12 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects between 18 to 65 years old.

Exclusion criteria

Exclusion criteria: 1)Subjects who regularly consume foods containing a dairy ingredient to be evaluated. 2)Subject who plans or wish to get vaccinated or donate blood during the test period. 3)Extremely heavy drinkers (more than 60g/day of alcohol). 4)Subjects who can not sleep at night due to irregular work or other reasons. 5)Subjects who take medicines or functional foods during the pre-test period, which might affect their subjective symptoms and/or immune function. 6)Subjects who can not stop taking medicines or functional foods during the test period, which might affect their subjective symptoms and/or immune function. 7)Subjects who have serious disease in the liver, kidney heart, lung, gastrointestinal tract, blood, endocrine system, or metabolic system etc. Or those who have serious medical history of these. 8)Subjects having chronic disorders. 9)Subjects who are positive in the pathogen test. 10)Subjects who need the application of medicine containing steroids. 11)Subjects having a milk allergy. 12)Subjects who have medical history of drug allergy or severe food ones. 13)Subjects who are pregnant or under lactation, or who is expected to be pregnant during the study. 14)Subjects who donated 400 mL of their blood within 12 weeks before the beginning of test-food intakes, or not less than 200 mL of their blood during the pre-test period. 15)Others who have been determined as ineligible for the research subject of this study, judging from the principal researcher/doctor's opinions on the findings of their background, physical observations, medical checkup, physical/clinical examination, and so on.

Design outcomes

Primary

Measure	Time frame
Subjective symptoms	—

Secondary

Measure	Time frame
Immune indices	—

Countries

Japan

Contacts

Public ContactMasahiko Kurokawa

Kyushu University of Health and Welfare Graduate School of Clinical Pharmacy

b2mk@phoenix.ac.jp982-23-5574

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026