Effect of Positive End-expiratory Pressure on Emergence from General Anesthesia: A randomized controlled trial

Effect of Positive End-expiratory Pressure on Emergence from General Anesthesia: A randomized controlled trial - Effect of Positive End-expiratory Pressure on Emergence from General Anesthesia: A randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048063

Enrollment

Registered

2022-07-01

Start date

2022-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery requiring general anesthesia

Interventions

With positive end-expiratory pressure (PEEP) Without positive end-expiratory pressure (PEEP)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing general anesthesia, ASA (American Society of Anesthesia) PS (Physical Status) 1-2

Exclusion criteria

Exclusion criteria: Cases that informed consent can not be obtained, Patients with respiratory disease, Patients with cardiac disease, Patients with neuropsychiatric disease, Patients with hepatic/renal disease, Patients with metabolic disorders, Cases of malignant hyperthermia, Cases of emergency surgery

Design outcomes

Primary

Measure	Time frame
Time from the end of anesthetic administration to awakening after the surgery is completed	—

Secondary

Measure	Time frame
End-tidal volatile anesthetics concentration, partial pressure of exhaled carbon dioxide, Bispectral index (BIS)	—

Countries

Japan

Contacts

Public ContactMichiko Kinoshita

Tokushima University Hospital Department of Anesthesiology

michiko-kinoshita@tokushima-u.ac.jp088-633-7181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026