Effect of vitamin D supplementation on muscle mass and function among sarcopenic elderly adults with vitamin D insufficiency: a randomized controlled trial

Effect of vitamin D supplementation on muscle mass and function among sarcopenic elderly adults with vitamin D insufficiency: a randomized controlled trial - vitamin D supplementation on sarcopenia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048060

Enrollment

226

Registered

2022-06-14

Start date

2021-04-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopenia

Interventions

1000 IU vitamin D3 600IU vitamin D3 placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)participants over 60 years with insufficient vitamin D [serum 25(OH)D concentrations <75nmol/L]. (2)participants with sarcopenia.

Exclusion criteria

Exclusion criteria: (1) taking vitamin D supplements. (2) participants with severe depression, cognitive impairment, cardiovascular and cerebrovascular diseases (stroke and myocardial infarction), cancer, impaired hepatic function, impaired renal function, and other serious metabolic diseases. (3) unable to complete the follow-up.

Design outcomes

Primary

Measure	Time frame
The differences in serum 25(OH)D, grip strength, gait speed, and relative skeletal mass index changes.	—

Countries

Asia(except Japan)

Contacts

Public ContactXuena Wang

Tianjin Medical University Nutrition and epidemiology institution

wangxuena_1214@163.com+86(0)22-83336613

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026