Effect of vitamin D supplementation on glucose homeostasis among Type 2 Diabetic patients: A Randomized Clinical Trial

Effect of vitamin D supplementation on glucose homeostasis among Type 2 Diabetic patients: A Randomized Clinical Trial - BETA CELL FUNCTION OR INSULIN SECRETION (HOMA B) The amount of glucose cleared from the blood in response to a dose of insulin. A score of less than 100 defined reduced B cell function. INSULIN RESISTANCE (HOMA IR) Defined as a condition when normal amount of insulin in body fails to produce the desired response . A score of greater than or equal to 2.0 defined IR. INSULIN SENSITIVITY Insulin sensitivity calculate by using the following formula is IS equal to 1 per IR (Normal is less than 3.0) VITAMIN D STATUS Vitamin D status was defined as SUFFICIENT with level of vitamin D greater than 30ng per ml and DEFICIENT with level of serum 25 (OH) vit D less than or equal to 30ng per ml.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000048031

Enrollment

146

Registered

2022-06-25

Start date

2019-05-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetic patients

Interventions

Vitamin D Supplementation Placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Type 2 diabetic patients of aged 30 year to 70 year who were in treatment of oral hypoglycemic agent. 2. Agreed to maintain their usual dietary and physical activity habits at the time of intervention. 3. Voluntarily willing to participate in this clinical study.

Exclusion criteria

Exclusion criteria: 1. Below 30 years or above 70 years of age with Type I Diabetes Mellitus on insulin 2. Consuming vitamin D supplements within 3 months before beginning of the study 3. Women patients who were pregnant or breastfeeding

Design outcomes

Primary

Measure	Time frame
HYPOTHESIS - ACCEPTED 1. Vitamin D supplementation for 12 weeks would improve glycemic indices of HbA1c among Type 2 diabetic patients as compared to placebo group 2. Vitamin D supplementation for 12 weeks would improve glycemic indices of fasting blood glucose among Type 2 diabetic patients as compared to placebo group	—

Secondary

Measure	Time frame
HYPOTHESIS - REJECTED 1. Vitamin D supplementation for 12 weeks would improve fasting Plasma Insulin.	—

Countries

Asia(except Japan)

Contacts

Public ContactNadia Begum

University of Dhaka, Bangladesh Institute of Nutrition and Food Science

nadiabegum.zhs@gmail.com+8801712929996

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026