Effect of a functional food supplementation on premenstrual water retention symptoms in women: a randomized, double-blind, placebo-controlled pilot study

Effect of a functional food ingredient on water retention symptoms in women with water retention symptoms in the luteal phase: a randomized, double-blind, placebo-controlled pilot study - Effect of a functional food supplementation on water retention symptoms

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047989

Enrollment

Registered

2022-06-10

Start date

2014-06-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Oral intake of a functional food ingredient, twice a day for 7 to 15 days Oral intake of placebo, twice a day for 7 to 15 days

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Premenopausal healthy women with normal menstrual cycle 2) Individuals who have cyclically onset or worsening of water retention symptoms during the luteal phase 3) Individuals who be able to understand the procedures 4) Individuals who agree to participate in the study by signing the informed consent

Exclusion criteria

Exclusion criteria: 1) Individuals who are pregnant, breast-feeding or intending to become pregnant 2) Individuals who have or had a history of an acute or chronic severe condition 3) Individuals who have a clinically relevant finding on the physical examination or blood testing 4) Individuals who take any continuous medications or dietary supplements

Design outcomes

Primary

Measure	Time frame
VAS scores of premenstrual symptoms on day 6, 7 and 8 of supplementation	—

Countries

Japan

Contacts

Public ContactHiroshi Tsukikawa

Medical Co. LTA Sugioka Memorial Hospital Planning and Coordination Dept

hiroshi-tsukikawa@lta-med.com092-662-3608

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026