Study for overcoming the severe infertility by new indole compound (MA-5)

Study for overcoming the severe infertility by new indole compound (MA-5) - Study for overcoming the severe infertility by new indole compound (MA-5)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047964

Enrollment

Registered

2022-07-01

Start date

2022-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility patients

Interventions

None listed

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Infertility patient, No matter reason for infertility, Age between 20 to 42, Male

Exclusion criteria

Exclusion criteria: Patient who has infection, such as hepatitis B virus, hepatitis C virus, Syphilis and HIV. Patient who has been registered to other clinical study. Patient who are using supplement drugs which affects mitochondrial function, such as Vit C&E, CoQ10 etc. Sample may not be used if the sperm parameter is not enough to analyze, even if patient eligible to enter this study and agreed.

Design outcomes

Primary

Measure	Time frame
Using discarded sperm, effect of MA-5 exposure is evaluated for sperm function (kinetics and fertilization ability) and mitochondrial function (ART production), and it is compared with non-treated counterpart.	—

Countries

Japan

Contacts

Public ContactMasahito Tachibana

Tohoku university hospital Dept of OB/GYN

masahito.tachibana.c1@tohoku.ac.jp0227177254

Outcome results