Clinical research to evaluate beta-amyloid deposition in the brain of patients with Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB)

Clinical research to evaluate beta-amyloid deposition in the brain of patients with Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB) - Amyloid PET studies in PDD and DLB

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047904

Enrollment

Registered

2022-05-31

Start date

2022-05-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with PDD or DLB who are attending or being admitted to the Department of Neurology, Juntendo University Hospital, Juntendo University School of Medicine, will be included in the study. PDD is diagnosed as Clinically Established PD or Clinically Probable PD by MDS Clinical Diagnostic Criteria for Parkinson's Disease, and PDD is defined as the onset of Dementia 2 years later. DLB is defined as patients diagnosed with Probable DLB (almost certain) by the Clinical Diagnostic Criteria for Dementia with Lewy Bodies (2017) Amyloid PET and neuropsychological testing can be performed For whom 123I-Ioflupane SPECT testing has been performed IMP-SPECT test performed has been performed

Exclusion criteria

Exclusion criteria: Age less than 40 years and greater than 81 years at the time consent was obtained Patients with more than moderate multiple cerebral infarctions Those with a history of epileptic seizures within 2 years Other subjects deemed inappropriate as research subjects by the principal investigator

Design outcomes

Primary

Measure	Time frame
beta-amyloid deposition in the brain	—

Countries

Japan

Contacts

Public ContactNoriko Nishikawa

Juntendo University School of Medicine Department of Neurology

n.nishikawa.ts@juntendo.ac.jp03-3813-3111

Outcome results