Effectiveness of rehabilitation during neoadjuvant chemotherapy on postoperative exercise capacity in patients with esophageal cancer

Effectiveness of rehabilitation during neoadjuvant chemotherapy on postoperative exercise capacity in patients with esophageal cancer - Effectiveness of rehabilitation during neoadjuvant chemotherapy on postoperative exercise capacity in patients with esophageal cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000047895

Enrollment

Registered

2022-05-30

Start date

2022-06-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cacner

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: [NAC group] 1. Patients who has been diagnosed with esophageal cancer 2. Patients who are scheduled for esophagectomy by standby surgery 3. Patients who started rehabilitation after completion of the first NAC course and before the start of the second NAC course [Control group] 1. Patients who has been diagnosed with esophageal cancer 2. Patients who are scheduled for esophagectomy by standby surgery 3. Patients who started rehabilitation after 2 NAC course

Exclusion criteria

Exclusion criteria: [Both group] 1. Patients with cerebrovascular, musculoskeletal disease and cognitive impairment that would affect the performance of the evaluation 2. Patients with complications requiring treatment during chemotherapy and postoperatively 3. Patients with less than 2 courses of NAC 4. Patients who have undergone radiation therapy 5. Patients who have difficulty communicating because they do not understand the purpose of the study 6.Patients who are deemed inappropriate as research subjects by the researcher

Design outcomes

Primary

Measure	Time frame
6-minute walk distance (6MWD)	—

Secondary

Measure	Time frame
QOL (EORTC QLQ-C30) Muscle strength (hand grip strength, quadriceps force) Skeletal muscle mass (PMI) Fatigue (CFS) Nutritional Status (GNRI, weight)	—

Countries

Japan

Contacts

Public ContactRyo Kozu

Nagasaki University Graduate School of Biomedical Science Department of Physical Therapy Science

ryokozu@nagasaki-u.ac.jp095-819-7963

Outcome results