Research on surgical anastomosis of the rectum

A Multicenter Randomized Controlled Trial Comparing Stapled and Hand-sewn Anastomosis in Intersphincteric Resection with Transanal Total Mesorectal Excision - Super SST Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047818

Enrollment

110

Registered

2022-05-31

Start date

2022-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal cancer

Interventions

Group A: Hand-sewn anastomosis Group B: Stapled anastomosis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged between 20 and 80 years old who are scheduled to undergo ISR with TaTME for rectal cancer located within 6cm from the anal verge (AV) will be included.

Exclusion criteria

Exclusion criteria: Emergent surgery, two or more anastomosis in the same surgery, poorly controlled diabetes mellitus, and cases deemed unsuitable by the doctor in charge, will result in exclusion.

Design outcomes

Primary

Measure	Time frame
Anastomosis-related complications within 30 days after surgery	—

Secondary

Measure	Time frame
operation time; reoperation; mortality; length of postoperative hospital stay; readmission; incidence of anal pain and rectal mucosal prolapse; length of temporary stoma retention; the proportion of patients with a temporary stoma at 1 year after surgery; anorectal function at 1 year after surgery	—

Countries

Japan

Contacts

Public ContactDaichi Kitaguchi

National Cancer Center Hospital East Department of Colorectal Surgery

dkitaguc@east.ncc.go.jp0471331111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026