Use experience of opioid antagonists peripheral for endotracheal intubation patients

Use experience of opioid antagonists peripheral for endotracheal intubation patients - Use experience of opioid antagonists peripheral for endotracheal intubation patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000047809

Enrollment

600

Registered

2022-05-19

Start date

2023-12-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intubation patients

Interventions

Nardemedine Mesylate Hydrochloride 0.2mg 4days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: It is made an endotracheal intubation more than 72 hours A narcotic analgesic is used There is not a movement for three days

Exclusion criteria

Exclusion criteria: A gastrointestinal ulceration, diverticular disorders, an invasive digestion duct carcinoma, the disease with the risk of the gastrointestinal perforation including peritoneal metastases, the Crohn disease of cancer. Under 18 years old There is a movement within 72 hours Extubation within the 72:00 time, ICU discharge, discharge The patients with the diarrhea

Design outcomes

Primary

Measure	Time frame
Time to movement	—

Countries

Japan

Contacts

Public Contactryo ichibayashi

Toho University Medical Center Omori Hospital Department of Critical Care Center

ryou.ichibayashi@med.toho-u.ac.jp+81337624151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026