Healthy adult and Healthy elderly
Conditions
Interventions
Subjects must be able-bodied individuals who are able to obtain free and voluntary consent to participate in the research in writing from themselves. Subjects must be at least 20 years of age at the t
Sponsors
International University of Health and Welfare
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects must be able-bodied individuals who are able to obtain free and voluntary consent to participate in the research in writing from themselves. Subjects must be at least 20 years of age at the time consent is obtained.
Exclusion criteria
Exclusion criteria: Subjects must have a history of circulatory, respiratory, gastrointestinal, urological, or back pain disease, including surgery, in the past 5 years. The subject is currently in need of continuous hospital visits and medication. Subjects have difficulty in obtaining free written consent for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main outcome measure is the calculation of single-beat output, cardiac output, and heart rate to evaluate the differences in circulatory dynamics in each of the set postures. The single beat ejection fraction will be calculated from the left ventricular ejection time calculated from the chest impedance and heart sounds using the method of Bernstein et al. The heart rate is calculated from the electrocardiogram. Cardiac output is calculated from the product of single beat volume and heart rate. | — |
Secondary
| Measure | Time frame |
|---|---|
| From the continuous blood pressure, the blood pressure in each posture (systolic, diastolic, and mean blood pressure) is calculated. From mean blood pressure and cardiac output, peripheral vascular resistance can be calculated. In the elderly, arterial stiffness, decreased vagal activity, and decreased sensitivity to the vagal baroreceptor reflex occur. Therefore, it is expected that there will be differences in the way the circulation is regulated during the Farrar position between the young and the elderly. In this study, we will calculate the index of vagal modulation from heart rate variability analysis. From RR interval and continuous blood pressure, baroreceptor reflex sensitivity (sequence method) will be calculated. To examine the effect of aging on arterial stiffness, the Arterial Pressure volume Index (API), an index of arterial stiffness in the upper arm, is calculated from the reflected waves of a pressurized upper arm cuff. In addition, to evaluate the effect of postural changes and blood movement on abdominal compliance, we will measure the push-in reaction force of the abdomen using a biotissue hardness tester. | — |
Countries
Japan
Contacts
Public Contacttakuya furudate
International University of Health and Welfare Department of Occupational Therapy
Outcome results
None listed