rheumatoid arthritis
Conditions
Interventions
None listed
Sponsors
Nagasaki University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with undiagnosed arthralgia in the hands less than 12 months after the onset of symptoms and patients without anti-rheumatic drug introduction 2. (A) New patients: Among the patients who first visited the outpatient department of Nagasaki University Hospital between the date of permission of the director of the research institute and March 31, 2024, those who obtained the consent for a dental examination, or (B) Existing patients: 2010 Among the patients who first visited the outpatient department of Nagasaki University Hospital between January 1 and the research permission date, those who are currently in the hospital with preserved serum and preserved images of X-ray (hand/foot) / ultrasound (hand) or MRI (hand) within 2 months from the time of the first visit.
Exclusion criteria
Exclusion criteria: 1. Patients receiving anti-rheumatic drugs at the first visit and at the time of serum storage/imaging evaluation 2. Patients without residual teeth
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RA diagnosis within 12 months from the first visit | — |
Secondary
| Measure | Time frame |
|---|---|
| Associations between RA diagnosis and HLA-DRB1 SE, serum biomarkers, AMPAs, salivary microbiota composition, ultrasound (hand) / MRI (hand) abnormal findings | — |
Countries
Japan
Contacts
Public ContactShin-ya Kawashiri
Nagasaki University Graduate School of Biomedical Sciences N/A
Outcome results
None listed